Objective To explore the patterns of door-to-balloon(D2B) timefor percutaneous intervention (PCI) among acute ST elevation myocardial infarction (STEMI) patients, to find the influencing factors of D2B, and to provide a reference for workflow optimization in chest pain center. Methods A total of 222 patients who underwent PCI in the emergency department from December 1st,2017 to November 31st, 2018 were enrolled. The D2B time was divided into 5 segments (into the hospital door to the first Electrocardiogram, blood drawing to quick on-site test results, requesting a consultation from important relevant departments to arrival of doctors who responded to the request, doctor-patient communication to signing informed consent, patient entry into the intervention room to balloon expansion), and the distribution of the 5 segments was described, and the influencing factors of the D2B time were explored. Results D2B time in 83.3% of the patients met China′s chest pain center certification standards. The median D2B time was 76（interquartile range 64-89）min. Multiple linear regression analysis showed that age, transfer from non-PCI hospitals, ability to pay and patients′ knowledge level of the disease were major influencing factors of D2B time（P<0.05,P<0.01）. Conclusion The median D2B time of the STEMI patients meets China′s chest pain center certification standards. Attention should be paid to STEMI patients who are older, less able to pay the medical bill, have inadequate knowledge of the disease, and not transferred from non-PCI hospitals. Measure such as simplifying treatment processes, ramping up regional cooperation, need to be taken to further shorten D2B time.