Objective To explore the nursing dynamic human resource management mode in outpatient blood collection post and its practice effect. Methods We analyzed the post, established a standardized post quota system and an entry qualification and training system for blood collection dynamic post, then set up a nursing dynamic resource database, realized the information-based airport self-service job recognition, improved the quality evaluation and control system, and established a scientific job performance distribution system. Results After applying the nursing dynamic human resource management model in outpatient blood collection post for 3 years, the waiting time of blood collection for outpatients was significantly shorter than that before application of the model, the salary performance of the nurses in the blood collection dynamic post was significantly higher than other nurses, and their perceived professional benefit was significantly higher than before (P<0.01 for all), and the human cost of our hospital reduced. Conclusion The nursing dynamic human resource management in outpatient blood collection post is conducive to providing high quality and efficient nursing services, improving nurses′ perceived professional benefit and salary, and reducing human cost of hospital.