Objective To explore the effect of multidisciplinary team-led and emergency green channel management of patients with aortic dissection. Methods A total of 959 patients with acute aortic dissection were chronologically divided into a control group of 472 patients, and an experimental group of 487 patients.The control group were subjected to routine rescue mode, while the expe-rimental group to a multidisciplinary team-led and emergency green channel management mode.The lengths of emergency stay, the time from emergency visit to diagnosis, rate of emergency mortality and rate of hospitalization in the two groups were documented and compared.Results The length of emergency stay, the time from emergency visit to diagnosis were significantly shorter, rate of hospitalization were significantly higher in the experimental group, than in the control group （all P＜0.01）.Conclusion Multidisciplinary team-led and emergency green channel management of patients with aortic dissection could integrate the medical resources and improve efficiency of emergency treatment.