This study introduces the concept of time-limited trials （TLTs）, key elements, initiation framework, timing for initiation, frequency of application, and duration.It summarizes the implications of TLTs for critical care nursing in ICU in China, highlights the challenges encountered during the implementation of TLTs, and puts forward suggests.Additionally, the paper offers corresponding recommendations to advance the application of TLTs in ICU care for critically ill patients, aiming to enhance ICU nursing quality, optimize resource allocation, and improve patient outcomes and quality of life.