Objective To explore the latent profiles and the influencing factors of barriers to physical activity in elderly coronary artery disease （CAD） patients complicated with diabetes mellitus （DM）, so as to provide references for conducting targeted health management.Methods A total of 280 elderly patients with CAD combined with DM were recruited from the Department of Cardiovascular Medicine of 3 tertiary A hospitals by convenience sampling method.Then they were investigated by using a general information questionnaire, the Perceived Social Support Scale, the Chinese version of the Tampa Scale for Kinesiophobia Heart, the Patient Health Questionnaire-9 and the Chinese version of the Barriers to Appropriate Physical Activity in CAD Patients.Results Totally 261 elderly patients with CAD and DM were effectively investigated.The total score of barriers to physical activity was （38.96±11.41）.The participants′ barriers to physical activity were divided into three latent categories:low barriers-stable type （26.8%）, moderate barriers-low movement type（12.3%） and high barriers-low perception type （60.9%）.Multiple logistic regression analysis showed that, age, family monthly income per capita, exercise fear and depression were the influencing factors of barriers to physical activity in different categories of elderly CAD patients complicated with diabetes.Conclusion The level of bar-riers to physical activity in elderly CAD patients complicated with DM is at a medium to high level, and there is obvious population heterogeneity.Medical staff should take targeted intervention measures according to the disease characteristics of different categories of patients, so as to improve their physical activity ability.