Abstract:Objective To conduct a scoping review of the literature related to advance care planning (ACP) for adolescents and young adults (AYAs) with cancer, and to analyze the current state of research in this area.Methods Following the formulation of the research question, relevant literature was retrieved from the Cochrane Library, PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP Database, and SinoMed, covering the period from database inception to June 2024.Literature was screened according to inclusion and exclusion criteria, and data from the included studies were extracted, summarized, and analyzed.Results A total of 13 studies were included, comprising 2 cross-sectional surveys, 4 retrospective cohort studies, 5 randomized controlled trials (RCTs), and 2 mixed-method studies based on secondary analyses of RCTs.The existing literature indicated ACP participation rate among AYAs with cancer was between 37.0% and 74.1%.Relevant interventions included family-centered ACP interventions, the use of video decision support tools, and communication strategies with patients and their proxies or families regarding future medical decisions, which could enhance the consistency of end-of-life preferences between cancer patients and their proxies or families; however, further validation was needed regarding their impact on reducing patient anxiety and depression levels.Six ACP support tools suitable for AYAs with cancer were identified, and the timing of ACP interventions occurred at any stage of the cancer trajectory.Conclusion Participation rates in ACP among AYAs with cancer are suboptimal, and the effectiveness and timing of interventions warrant further investigation.Future research should focus on exploring the needs for ACP among AYAs with cancer, conducting clinical studies to validate intervention outcomes, developing localized and specific ACP tools, and identifying key intervention points.