Objective To translate the NAFLD-SMQ into Chinese, and to provide an effective and scientific measurement tool for the establishment of a health management system for this population in China.Methods The Chinese version of the NAFLD-SMQ was formed through translation, back-translation, cultural adaptation and pre-survey after obtaining the authorization from the original author.A total of 334 patients with non-alcoholic fatty liver disease were conveniently selected from fatty liver specialist clinics and physical examination centers of 2 tertiary hospitals in Shanghai from July 2022 to March 2023 for questionnaire survey, aiming to evaluate the reliability and validity of the scale.Results The Chinese version NAFLD-SMQ contains 6 dimensions and 22 items.Exploratory factor analysis extracted 6 factors, the cumulative variance contribution rate was 74.254%, and the confirmatory factor analysis showed that the model was fitted.The scale-leve content validity index (S-CVI/UA) was 0.863, Cronbach′s α coefficient of the Chinese version was 0.920, and the Cronbach′s α coefficients of each dimension ranged from 0.830-0.942.The test-retest reliability of the Chinese version of NAFLD-SMQ 0.906 for the whole scale and 0.733-0.835 for all dimensions.Conclusion The Chinese version of NAFLD-SMQ shows good reliability and validity and can be used as an effective tool to evaluate the level of self-management in patients with nonalcoholic fatty liver disease.