Objective To standardize the methods of lymphedema specialist nursing, and to provide specialized, homogenized and systematic lymphedema specialist nursing for patients. Methods A specialist nursing team was set up for patients with lymphedema in the whole hospital, the responsibilities of the team were established, the quality control of the specialist was implemented, and the clinical work, training and teaching work run and were managed stardardly, including specialist nursing outpatient service, group manual drainage and complete decongestive therapy, case management and extended nursing, in-hospital and out of hospital consultation. Results In the past three years, more than 4 550 outpatient visits, 1 532 network consultations and 3 753 Complete Decongestive Therapy (CDT) were conducted in the Lymphedema Rehabilitation Center. The satisfaction survey of 2 600 patients treated with CDT was 96.84%. Conclusion The management and operation mode of lymphedema specialist nursing team meets the rehabilitation needs of lymphedema patient, and promots the development of lymphedema specialized nursing.