Objective To develop and validate the reliability and validity of the Patient-reported Functional Outcomes Scale for Patients after Partial Laryngectomy, and to provide a reference for accurately assessing the functional status of patients and formulating effective rehabilitation training programs. Methods According to the guidelines of Patient-reported Outcomes Measures, a pre-test scale was formed through literature review, semi-structured interviews, expert consultation and patient cognitive interviews.A total of 410 patients after partial laryngectomy for laryngeal cancer from 4 general hospitals were conveniently selected for survey.Survey data were used for item analysis and to test reliability and validity of the scale. Results The formal scale contained 3 dimensions（swallowing function, voice function, and respiratory function） and 21 items, and the cumulative variance contribution rate of the 3 common factors was 69.794%.Confirmatory factor analysis showed that the fit indexes were good.The content validity index of the whole scale was 0.980, and the correlation coefficients between each dimension and the total score was 0.655-0.840.The Cronbach′s α coefficient was 0.928, the split-half reliability coefficient was 0.734, and the test-retest reliability coefficient was 0.846. Conclusion The scale has good reliability and validity. It can be used as a valid tool to assess the functional outcome for patients after partial laryngectomy.