This paper summarizes contents of patient-reported outcome (PRO) in breast cancer-related lymphedema (BCRL) , measures, and application effects. It introduces diverse characteristics and application features of PRO measures in BCRL patients, analyzes selection of PRO measures for different research aims, and proposes the application methods of PRO in lymphedema, aiming to provide reference for the development of PRO measures for Chinese BCRL patients, as well as for symptom management and clinical decision-making.