Objective To explore the effect of a novel position-turning pad in critical patients with neurologic disease. Methods A total of 199 critical patients admitted to the neurosurgery department were divided into a control group (n=101) and an observation group (n=98) according to their admission time. The control group used conventional position turning pad, while the observation group used a novel position turning pad. Results The comfort degree, operative time for position turning, length of postural maintenance and the rate of pressure injury in the observation group were significantly better than those in the control group(all P<0.05). Conclusion The application of novel position turning pad can improve patient comfort, reduce pressure injury and enhance the efficiency of postural care.