Objective To understand the resilience experience of adolescents with type 1 diabetes, and to provide references for clinical medical staffs to formulate targeted intervention strategies. Methods Semi-structured interviews with 15 adolescents with Type 1 diabetes from two tertiary A hospitals in Nanjing were carried out per hermeneutic phenomenology.Benner′s analysis method was applied to extract themes from the interview data. Results The resilience experience in adolescents after diabetes diagnosis were divided into three stages of generation, coping and outcome, and 3 themes were extracted.Theme 1:reject type 1 diabetes （burden of disease management, physical health threats, changes in body image, and emotional and social isolation）; theme 2:maintaining a normal life （cognitive restructuring and emotional regulation，and solving problems and achieving development）; Theme 3:gaining hope and strength （hopeful future and post-traumatic growth）. Conclusion Endocrinology medical staff should pay attention to the resilience experience of adolescent with type 1 diabetes in the course of illness, and give targeted guidance and intervention to promote their disease adaptation and well-being.