Objective To construct and implement the training scheme of escape room themed nursing skill competition training, and to explore the participation experience of nursing students. Methods Semi-structured interviews were conducted with 15 nursing undergraduates who participated in escape room themed nursing skill competition training, and the data were analyzed by using content analysis method. Results Two themes were extracted:learning effect and learning feedback.The learning effect included five sub-themes:stimulating learning interest, strengthening operation skills, improving clinical thinking, enhancing team working and perceiving humanistic care;learning feedback included four sub-themes:the rigor of details needed to be improved, the authenticity of situations needed to be enhanced, the diversity of forms needed to be enriched and the diversity of subjects needed to be broa-dened. Conclusion The training of skill competition in escape room brings positive experience to nursing students, and it needs to be improved to further consummate the training program.