Objective To improve transformational leadership of head nurses in comprehensive hospitals and nurses′ satisfaction with head nurses. Methods A transformational leadership training team was established.The team provided theoretical and practical teaching of leadership improvement training for all head nurses in the hospital according to the five stages of ADDIE model.The training modules included in-hospital theory course, out-of-hospital learning and hands-on practice.Transformational leadership scores of head nurses and the satisfaction of the nurses were evaluated and compared before and after the training. Results After the training, the total score of transformational leadership, and scores of personalized caring ability and intelligent stimulation dimensions significantly improved as compared to those before the training; the satisfaction of nurses with head nurses also saw significant improvement （all P＜0.05）. Conclusion Transformational leadership training based on ADDIE model can improve transformational leadership of head nurses, and effectively improve nurses′ satisfaction with head nurses.