Objective To develop an information-based transfer form for critically ill patients in emergency department, and to evaluate its application effect. Methods A research team was set up, and an information-based transfer form with three function modules (adding, filling, analyzing) was designed. Then 200 patients in the emergency room were selected by conve-nience sampling and were chronologically divided into a control group and an experimental group, with 100 patients in each group.The control group used traditional paper transfer form, while the experimental group utilized the designed information-based transfer form. Results The writing quality of the transfer form in the experimental group was significantly higher than that of the control group, after application of the information-based transfer form, shifts nurses′ satisfaction on handing-off was significantly better than that before application, and the frequency of re-checking or confirming patients′ information was significantly reduced (all P<0.05). Conclusion Application of the information-based transfer form for emergency critically ill patients can improve the writing quality of the transfer form, reduce the number of re-checking patients′ information repeatedly, and improve nurses′ work efficiency and satisfaction.