Objective To explore the application effect of perioperative graded exposure exercise in lumbar disc herniation patients with Kinesiophobia. Methods A total of 80 patients with kinesiophobia who underwent lumbar intervertebral disc extraction, bone graft and internal fixation were chronologically divided into a control group and an experimental group, with 40 patients in each group. The control group was given routine perioperative nursing care for lumbar disc herniation, while the experimental group additionally received graded exposure exercise for 3 months. Results In the two groups, the intervention effect, time effect, time×intervention interaction effect in kinesiophobia scores were significant, the intervention effect and time effect in the JOA scores were significant, and the improvement of treatment in the experimental group during hospitalization was significantly better than that in the control group, and its compliance of functional exercise was significantly higher than that of the control group (all P<0.05). Conclusion Graded exposure exercise is beneficial for reducing lumbar disc herniation patients′ postoperative fear of movement, improving their compliance of low back muscle functional exercise and postoperative lumbar function.