Objective To construct a hospital-community-family cooperative service model of "Internet plus maternal and infant home care", and evaluate its application effect. Methods An "Internet plus Maternal and Child Care Innovation Platform" was developed. Relying on this Internet platform, a certain tertiary obstetrics and gynecology hospital took the lead and provided homogenized training for community hospitals in its jurisdiction, and then they jointly provided maternal and child care services such as breastfeeding guidance for home-based mothers and newborns. Results After seven months of operation, a total of 916 cases were completed, with a repurchase rate of 37.56%, of which 45 cases (4.91%) were completed by community nurses, and the top three service items were 460 cases (50.22%) of breast dredging, 318 cases (34.72%) of infant jaundice measurement, and 52 cases (5.68%) of breastfeeding guidance. Patient satisfaction was 99.82%, and no adverse nursing events or nursing-patient disputes occurred. Conclusion The hospital-community-family cooperative service model of "Internet plus maternal and infant home care" can provide convenient, fast and professional homogeneous hospital nursing services for home-based mothers and newborns.