Objective To summarize the best evidence for umbilical cord management in normal full-term neonates after birth, and to provide a reference for clinical practice decision-making. Methods Clinical decisions, clinical practice guidelines, expert consensus, evidence summaries and systematic reviews related to neonatal umbilical cord management in the past decade were systematically retrieved, and their methodological quality was evaluated. Then, the data were extracted, analyzed and summarized into the best evidence summary. Results A total of 21 articles were included: 1 clinical decision, 16 guidelines, 3 expert consensus and 1 systematic review.A total of 24 pieces of best evidence were summarized, including 5 aspects: cord clamping, cord extrusion, cord examination, cord care and respecting women′s wishes. Conclusion Summary of the best evidence for umbilical management of normal full-term infants after delivery can provide a basis for clinical decision-making. In the future, it should be combined with specific clinical situations, and fully considering women′s wishes to maximize the benefits of mother and child.