Objective To investigate the effect of somatosensory-controlled speech rehabilitation training system on speech rehabilitation in tongue cancer patients after surgery. Methods Seventy-eight tongue cancer patients with speech dysfunction after surgery were chronologically assigned to two groups, with 39 in each group. The control group was given usual rehabilitation training, while the observation group received speech rehabilitation training using a somatosensory-controlled system. Results Six months after the intervention, the scores of speech intelligibility and quality of life in the observation group were significantly higher than those in the control group (all P<0.05). Conclusion Application of intelligent speech rehabilitation training system can improve rehabilitation effect and quality of life in patients after tongue cancer surgery.