Objective To systematically analyze studies in return to work(RTW) intervention for breast cancer survivors , to identify specific contents, outcomes and effects of intervention, so as to provide guidance for medical staff. Methods A literature search was performed in the CNKI, Wanfang, VIP, CBM, CINAHL, Pubmed, Embase，Web of Science to identify relevant studies published during the establishment of the database to June 22, 2022.The included studies were summarized and analyzed. Results Totally 12 studies were included, of which 11 were randomized controlled trial and 1 was prospective longitudinal study.RTW intervention plans included vocational rehabilitation, exercises and multidisciplinary team-based vocational rehabilitation interventions.Intervention forms included offline interventions, online interventions and a combination of online and offline interventions. The frequency of interventions tended to be 1-3 times per week, with a duration of 6 or 12 months. The results showed that interventions had varying degrees of influence on RTW related outcomes, psychological status, and clinical outcomes. Conclusion RTW intervention is holistic, individualized and the effects are not yet clear.Future research should focus on exploring more effective interventions strategies, developing standardized and uniform evaluation criteria, and formulating scientific and applicable programs based on the physical status and willingness of breast cancer survivors.