Objective To develop the Symptom Cluster Assessment Scale for Gout Patients and to provide a tool for clinical professionals to effectively assess the symptoms of gout patients. Methods Based on the Symptoms Experience Model, we developed the first draft of the scale through literature review, semi-structured interviews and Delphi expert consultation.Thirty patients with gout were selected for pilot test, and the scale was further revised according to patient feedback.Respectively 170 and 272 patients with gout were conveniently selected for the first and second round of survey to test the reliability and validity of the scale. Results The final version of the Symptom Cluster Assessment Scale for Gout Patients included 22 items.Six common factors (joint symptom cluster, movement limitation symptom cluster, psycho-sleep symptom cluster, urinary system symptom cluster, systemic manifestation symptom cluster, gouty stone symptom cluster) were extracted by exploratory factor analysis, accounting for 67.301% of the total variance.Confirmatory factor analysis indicated that factor structure of the scale was good (χ2/df=2.680, SRMR=0.076, RMSEA=0.079, CFI=0.903, TLI=0.884).The item-level content validity index was 0.833-1.000, and the scale-level content validity index was 0.889.Cronbach′s α, split-half reliability and test-retest reliability coefficients were 0.863, 0.836, and 0.947 respectively. Conclusion The Symptom Cluster Assessment Scale for Gout Patients has good reliability and validity and it is suitable for symptom assessment in gout population.