Objective To retrieve, evaluate and summarize the best evidence on self-care of lower-limb lymphedema after surgery for cervical cancer, so as to provide reference for clinical nursing practice. Methods Following the 6S evidence pyramid model, electronic databases or websites were searched for literature regarding self-care of lower-limb lymphedema after surgical treatment of ce-rvical cancer from database inception to January 2022.The literature included computerised decision support systems report, guideline, evidence summary, clinical practice recommendations statement, systematic review, and expert consensus statement. Results A total of 11 publications were eligible, including 1 decision support system report, 3 guidelines, 3 systematic reviews, 1 evidence summary and 3 expert consensus statement reports. Twenty-three pieces of evidence were identified, embracing three aspects (risk factors, self-care measures, health education and follow-up) and ten subthemes. Conclusion Clinical medical staff should consider specific clinical situation to select the best evidence, and provide scientific nursing guidance for patients with lower-limb lymphe-dema, thus to improve their self-care ability.