Objective To understand the lived experience of family caregivers caring for adolescents with mental disorders associated with non-suicidal self-injury behavior, and to provide references for formulating family intervention strategies. Methods This study followed phenomenological approach to describe the experience of ten family caregivers.Data were collected using individual, seme-structured, in-depth interviews.The interview transcriptions were analyzed using Colaizzi′s method. Results Four themes of family caregivers′ experience emerged, including insufficient cognition of non-suicidal self-injury, high family pressure, complex negative emotions, reflection and growth. Conclusion It is necessary to popularize the knowledge of adolescent non-suicidal self-injury, pay attention to caregivers′ psychological burden, strengthen family intervention, and improve mental health of caregivers.