Objective To design and explore the effect of implementing ideological and political theory education in the course of Nursing Aesthetics. Methods Ideological and political theory education was carried out among 47 junior nursing students who selec-ted the course of Nursing Aesthetics.The ideological and political theory education mode was developed by building up a teaching team that included faculty and clinical staff, resetting the teaching objectives and contents based on ideological and political elements mining, and designing immersive and creative teaching activities.At the end of the course, the teaching effect was evaluated by investigating students′ perception of ideological and political education and their recognition of teaching activities, and understanding students′ experience of course participation. Results Overall, 83.0%-97.9% students had good perception of the teaching effect, and 70.2%-91.5% recognized the teaching activities.Three themes were derived in terms of learning experience: natural combination of ideological and political elements and professional knowledge, diverse teaching activities and high level of participation, and the teaching mode playing a positive role in value shaping. Conclusion Implementation of ideological and political theory education in the course of Nursing Aesthetics helps cultivate students′ aesthetic accomplishment, professionalism and humanities. The teaching mode was widely recognized by students.