Objective To form an expert consensus report on the prevention of intraoperatively acquired pressure injury (IAPI), and to provide a practical guidance for the prevention of IAPA in surgical patients. Methods Through literature retrieval, the evidence and expert recommendations related to intraoperative pressure injury prevention were extracted, and the first draft of the expert consensus report was formed.The first draft was then revised and refined through two rounds of expert consultation and four times of online meetings. Results The expert consensus report on the prevention of IAPA includes six aspects:risk factors and nursing assessment of acquired pressure injury, selection of assessment tools, selection of assessment timing, risk definition and classification, graded prevention and management. Conclusion Based on evidence and guidelines, this consensus is constructed through evidence-based methods, which is operable and practical, and can provide theoretical basis and practical guidance for the IAPA prevention of surgical patients and the nursing management of operating room.