Objective To translate the Infection Prevention Society (IPS) Competency Framework into Chinese, to provide a new theoretical framework for research in the field of infection prevention and control. Methods The IPS Competency Framework was translated and back-translated to form a Chinese version. Then 19 experts were involved in two rounds of Delphi consultation. Results The response rates of the two-round consultations were 90.48% and 94.74%, respectively; experts′ authority coefficients were 0.871 and 0.881 respectively; Kendall′s coefficients of concordance were 0.144 and 0.204 respectively（P<0.01）. The Chinese version IPS Competency Framework includes 4 domains (clinical practice competence, learning and education competence, quality improvement and research competence, leadership and management competence ) and 15 items. Conclusion The experts had high approval of the Chinese version IPS Competency Framework, which could provide a reference for competency training and evaluation of nurses in the field of infection prevention and control.