Objective To investigate the status and influencing factors of social alienation in cervical cancer survivors， and to provide reference for implement of targeted intervention measures. Methods A total of 395 cervical cancer survivors were selected as the research objects and surveyed using the general situation questionnaire, the General Alienation Scale, the Social Impact Scale and the Social Support Rating Scale. Results The cervical cancer survivors scored (41.98±6.81) points in social alienation; per-capita monthly family income, time since last treatment, stigma (as measured with Social Impact Scale), and social support were the main influencing factors of social alienation, with the above-mentioned variables collectively explaining 46.1% of the total variance. Conclusion Social alienation in cervical cancer survivors was at a moderate level. Medical staff should pay attention to social alienation assessment in cervical cancer survivors, especially for patients with lower income and shorter time since last treatment, and seek to reduce the level of stigma and improve the level of social support, in a bid to reduce their social alienation level.