Objective To establish trauma team activation criteria for Jiangsu provincial trauma center. Methods Using the National Trauma Triage Protocol in the United States as the basic framework, we searched domestic and foreign databases to obtain publications related to the trauma team activation criteria that are helpful in identifying patients with severe trauma, and drafted a preliminary version of trauma team activation criteria for Jiangsu provincial trauma center. Then we conducted Delphi expert consultation regarding the activation criteria and used hierarchy analytic process (AHP) technique to establish the weight of each item. Results The expert questionnaire response rate was 92.0%, and 100.0%, and expert authority coefficient was 0.91 and 0.93, for the first and second round of consultation respectively; Kendall′s coordination coefficients ranged 0.183-0.245, and 0.153-0.311 for the first and second round, respectively (P<0.05 for both). The final version of trauma team activation criteria included 4 first-level items, 30 second-level items. Conclusion The trauma team activation criteria for Jiangsu provincial trauma center are scientific and reliable, and can identify patients with severe trauma .The criteria provide prompt and correct guidance regarding trauma team activation.