Objective To explore the effect of whole course management on recovery of patients developing dysphagia after acoustic neuroma surgery. Methods A whole course management group was established, and 56 patients developing dysphagia after acoustic neuroma surgery were selected as research participants and divided into 2 groups according to chronological order of hospitalization. The control group (n=28) received routine nursing care, while the intervention group (n=28) was subjected to whole course management led by the case manager. Results At one year into the intervention, there were significant main effects for time, group-by-time interaction and group on medication compliance, rehabilitation compliance, and swallowing function scores between the two groups (all P<0.05). There were significant main effects for time and group on quality of life scores (all P<0.05). Conclusion Whole course management can effectively improve medication and rehabilitation compliance of patients developing dysphagia after acoustic neuroma surgery, promote recovery of swallowing function and improve their quality of life.