Objective To summarize the relevant evidence of intradialytic exercise for maintenance hemodialysis (MHD) patients. Methods Following the evidence pyramid model, we electronically searched databases for literature relevant to intradialytic exercise from inception to 31 July, 2021.Methodological quality of the literature, levels of evidence and grades of recommendation were made using the assessment tools of the Joanna Briggs Institute （JBI）. Results One guideline, 1 expert consensus report, and 9 systematic reviews were included.Thirty-eight pieces of evidence were identified and categorized into 10 aspects:the necessity of intradialytic exercise, contraindications, safety, benefits, duration, frequency, intensity, procedures, guidance/monitoring, and precautions. Conclusion The evidence of intradialytic exercise for MHD patients is comprehensive and practical, which can be used by hemodialysis nurses in nursing practice.