Objective To explore the strategies for cultivating nutrition support nurse. Methods A training framework was developed based on core competencies of nutrition support nurses, and then implemented in 115 trainees. The training included 4-week theoretical lecture and 8-week clinical practice. Results The total score of performance in examination was (90.69±2.28) and 98.26% of the trainees were satisfied with the training. Conclusion The nutrition support nurse training program can enhance nutrition knowledge and skills of specialty nurses, thus to advance their continuous development.