Objective To explore current status and the influencing factors of oncology nurses′ hospice core competencies, and to provide references for targeted intervention strategies aiming at improving oncology nurses′ hospice core competencie. Methods A cross-sectional survey was conducted among 613 oncology nurses from 11 hospitals in Liaoning province by the Hospice Core Competencies Questionnaire for Oncology Nurses. Results The total score of core hospice competencies among the nurses averaged (123.30±27.09) points, with an item-level mean score of 3.08.The competence dimensions of education, collaboration and professional development and bereavement care, scored the lowest. Multivariate regression analysis showed that the level of hospice care services in the institution, love for hospice care, whether being qualified for hospice care, and whether having participated in training sessions on hospice care were influencing factors of nurses′ core hospice competence （P＜0.01 for all）. Conclusion Hospice care core competencies among oncology nurses are at medium level. Nursing managers should pay more attention to the education and core-competence-oriented training, in an effort to improve nurses′ end-of-life care competence and the quality of end-of-life care.