Objective To understand the level of knowledge of urgent management of stroke among citizens in Chengdu, and to explore the effect of health education. Methods A total of 638 citizens from 3 districts of Chengdu city were surveyed in terms of their knowledge toward urgent management of stroke, then health education was provided through WeChat, telephone and pamphlet. Their knowledge was tested again after the education. Results The total score of knowledge toward urgent management of stroke before health education was 23.95±6.53, with the scoring rate being 57.02%. Study of medicine and health sciences, wellness check, monthly income, and educational level were the factors affecting knowledge of urgent management of stroke. The knowledge score was significantly increased after the health education （P<0.01). Conclusion Knowledge toward urgent management of stroke among community dwelling people should be improved and the influencing factors are diverse. Health education can promote knowledge of citizens toward urgent management of stroke.