Objective To explore the effects of interactive group activity based management on cognitive function, ability of daily living and quality of life among community elderly patients with mild cognitive impairment (MCI). Methods Elderly patients with MCI were recruited in this quasi-experimental study and divided into 2 groups.The intervention group (n=35) received interactive group activity based management for 12 weeks, while the control group (n=36) received routine health guidance. All patients completed the Montreal Cognitive Assessment-Basic (MoCA-B), the Activity of Daily Living Scale and Quality of Life in Alzheimer′s Disease Scale (QoL-AD) at baseline and 12 weeks into the intervention. Results After the intervention, the scores of cognitive function and quality of life in the intervention group were significantly higher than baseline level and those of the control group （P＜0.01 for all）, and the scores of activity of daily living in the intervention group were lower than baseline （P＜0.05）, while showed no significant difference with those of the control group （P＞0.05）. Conclusion Interactive group activity based management, which integrates internet platform and offline community group activity, is an effective disease management model for patients with MCI living in community, and can improve patients′ cognitive function and quality of life.