Objective To investigate the effect of stone needle therapy on migraine patients with hyperactivity of liver Yang. Methods A total of 100 patients with migraine of hyperactivity of liver Yang were enrolled and randomly divided into 2 groups, and 91 patients (45 in the control group,46 in the intervention group) completed the study.The control group was given routine medical and nursing care, while the intervention group was given stone needle therapy in addition to routine nursing care. Results The headache scores at 12 weeks in the intervention group were significantly lower than in the control group; the short-term and long-term TCM syndrome efficacy of the intervention group was significantly better than that of the control group (P＜0.01 for all). Conclusion Stone needle therapy can effectively relieve symptoms of migraine patients with hyperactivity of liver Yang.