Objective To investigate the current status of foot risk screening among patients with diabetes, and to analyze the main factors affecting them screening foot risk regularly, in order to provide reference for conducting targeted intervention to promote diabetic foot risk screening. Methods A total of 1027 diabetic inpatients in endocrinology department from 32 general hospitals in Hunan province were selected using convenient sampling, who were then investigated utilizing a self-designed questionnaire on foot risk screening. Results Diabetic foot high-risk population accounted for 57.1%, while only 15.7% patients screened their feet regularly. The main reasons for non-regular screening were feeling not necessary, not convenient to go to hospital for examination, and did not mentioned by medical staff. Logistic regression analysis revealed that, gender, family personal monthly income, risk population of diabetic foot, recognition of screening necessity were the main influencing factors of regular foot risk screening in diabetic patients （P＜0.05,P＜0.01）. Conclusion The rate of regular foot risk screening in diabetic patients is low, the patients with a female gender, lower family personal monthly income, non-high risk population of diabetic foot and insufficient recognition of screening should be paid more attention, and targeted intervention should be carried out according to patients′ cognition, psychological construction and screening tool selection etc, so as to improve their compliance of regular foot risk screening.