Objective To understand the current status and influencing factors of physical activity among populations at high risk for stroke, and to provide basis for targeted intervention measures. Methods A total of 272 people at high risk for stroke from 4 communities in Shanghai were enrolled.The general information questionnaire, the Exercise Self-Efficacy Scale, the 9-item depression module of the Patient Health Questionnaire (PHQ-9), and International Physical Activity Questionnaire-Long Form were used to surveyed the participants. Results The median(IQR) of total weekly metabolic equivalent was 1 872（569,2 859） MET-min/w, and 69.5% were having moderate and above level physical activity. The main type of physical activity was housework (34.3%) and leisure exercise (41.6%). Multiple linear regression analysis results showed that age, gender, monthly household income and exercise self-efficacy were main influencing factors of physical activity in population at high risk for stroke （P＜0.05，P＜0.01）. Conclusion The level of physical activity in population at high risk for stroke is low, especially for those aged 40-59, being male, having high household income and low exercise self-efficacy. Targeted intervention should be given to improve the level of physical activity in high-risk population.