Objective To explore the effect of family-community-hospital coordinated treatment for patients with acute coronary syndrome (ACS). Methods A total of 124 patients with acute ST-segment elevation myocardial infarction were divided into a control group of 61, who received routine treatment, and an intervention group of 63, who received family-community-hospital coordinated treatment. Means of admission transport, length of pre-hospital phase, length of in-hospital phase,and clinical outcomes between the 2 groups were compared. Results The means of admission transport, the time from symptom to first medical contact, from admission to first ECG, from PCI decision to obtainment of informed consent, from informed consent to activation of the cardiac catheterization laboratory, from door to balloon, and from symptom to balloon, and clinical outcomes (except for mortality) between the 2 groups had significant differences （P＜0.05，P＜0.01）. Conclusion Family-community-hospital coordinated treatment program can shorten the rescue time of patients with ST-segment elevation myocardial infarction, reduce average hospital stay and hospitalization costs, and lower the rate of unplanned all-cause readmission within 30 days.