Objective To explore the impact of the Satir model guided training on perceived professional benefits of nurses. Methods A total of 120 nurses were randomized into a control group and an intervention group of 60, receiving either routine supportive psychological counseling or the Satir model guided training once a month, respectively. Perceived professional benefits of nurses in the two groups were measured before and 6 months after the training. Results The total score and dimension scores of perceived professional benefits in the intervention group were significantly higher than those in the control group after the training (P<0.05，P<0.01). Conclusion The practice of the Satir model guided training can enhance perceived professional benefits of nurses.