Objective To evaluate the methodological and reporting quality of guidelines and consensus statements on early mobilization in mechanically ventilated patients in the ICU, and to analyze the contents of early mobilization. Methods Electronic resources such as guideline databases, related organization websites and biomedical databases were searched to retrieve guidelines and consensus statements on early mobilization of ICU patients on mechanical ventilation. Four reviewers independently evaluated the methodological and reporting quality of the literature by using the Appraisal of Guidelines for Research & EvaluationⅡReporting Checklist (AGREEⅡ) and the RIGHT statement, then they analyzed and summarized the contents of early mobilization protocol. Results A total of 4 guidelines and 7 consensus statements were included, with 1 guideline of Grade A quality and the rest literature of Grade B quality. Early mobilization protocol consisted of 4 aspects of objectives, principles, risk screening, implementation and monitoring. Conclusion The methodological and reporting quality of the included guidelines and consensus statements are average, and high-quality evidence are needed to develop domestic guideline or consensus on early mobilization, thus to help medical professionals implement early mobilization in the ICU.