Objective To explore the correlation of bandaging method and therapeutic effect in patients with breast cancer-related lymphe-dema. Methods Sixty-two patients with breast cancer-related lymphoedema receiving complex decongestive therapy were randomized into 3 groups. The Figure-of-eight group received bandage treatment in a Figure-of-eight shape, the spiral group received bandaging in a spiral fashion, overlapping each previous wrap by one half, and the combination group received both bandaging methods for treatment. Circumference of the limb, extracellular water/total body water ratio, patient satisfaction and the rate of bandage loosening were compared among the three groups after 20 treatments. Results The circumference of the limb and extracellular water/total body water ratio were improved in all three groups after the treatment, and 3 items of patient satisfaction had significant difference among the three groups （P＜0.05 for all）. None of patients in the combination group developed bandage loosening. Conclusion All three bandaging methods achieve satisfactory outcomes in lymphedema, and the combination use of Figure-of-eight and spiral bandaging is more comfortable for patients without loosening of bandage and can enhance patient satisfaction.