Objective To explore the effect of information-motivation-behavioral skills (IMB) model-based discharge planning applied in colorectal cancer patients undergoing permanent colostomy. Methods Sixty patients with permanent stomas were assigned to a control group (n=30) or an intervention group (n=30) according to their hospitalization wards, receiving either routine nursing care or IMB model-based discharge planning. Results The total self-efficacy scores at discharge, 1 month and 3 months after discharge were significantly higher in the intervention group than those in the control group (P<0.01).The intervention group had lower incidence of stoma-related complications compared with the control group (P<0.05,P<0.01). Conclusion Implementation of IMB model-based discharge planning can enhance self-efficacy and reduce stoma-related complications in ostomy patients.