Objective To relieve the stress of young breast cancer patients in the transitional period, and to improve their quality of life and recovery. Methods Eighty young breast cancer patients within one year of surgery and radiochemotherapy were randomized into one of two groups, with 40 in each group. The control group was given routine rehabilitation education and follow-ups, while the intervention group received 8-week mindfulness-based cancer recovery intervention. The Perceived Stress Scale, Cancer Fatigue Scale and Functional Assessment of Cancer Therapy-Breast were employed to evaluate the effect before, immediately after and one month after intervention. Results Thirty-five patients in the control group and 37 in the intervention group completed the study. A significant group effect was observed for perceived stress score and quality of life score between the two groups, and a significant time effect for cancer-related fatigue score was also evident （P＜0.05 for all）. Conclusion Mindfulness-based cancer recovery intervention could effectively relieve perceived stress and enhance quality of life of young breast cancer survivors in the transitional period.