Objective To validate the effect of compression duration using radial artery compressor on complications after transradial coronary angiography. Methods Literature reporting randomized controlled trial （RCT） of compression duration using radial artery compressor after transradial coronary angiography were retrieved in international and national electronic databases from inception through May 1, 2020. After evaluation of the methodological quality of the literature, meta-analysis was conducted by RevMan5.3. Results A total of 8 RCTs with a total of 2 399 patients for analysis.Mata-analysis showed compression maintained for 1 h had lower incidence of pain and vasovagal reflex compared to compression maintained for 2 h （P＜0.05,P＜0.01）, and the significant difference in rate of radial artery occlusion was at threshold P value (P=0.05). Compression maintained for 1 h resulted in similar risk of bleeding, swelling,numbness,ecchymosis,blister and hematoma compared to compression maintained for 2 h （P＞0.05 for all）. Conclusion Compression maintained for 1 h using radial artery compressor after transradial coronary angiography could decrease the incidence of pain and vasovagal reflex, but the effect on radial artery occlusion needs more evidence.