Objective To investigate early mobility levels of patients undergoing laparoscopic radical cystectomy, and analyze the influencing factors. Methods A convenience sample of 92 patients receiving laparoscopic radical cystectomy were enrolled and their mobility within 24 hours after operation were assessed and, and the influencing factors of early mobility level were analyzed. Results Totally, 71.7% patients had low level of mobility, of which 50.0% were confined to bed rest. Comorbidity and preoperative activity level were the influencing factors of early mobility level after operation（P＜0.05，P＜0.01）. Conclusion Patients receiving radical cystectomy have low level of early mobility after operation. Medical staff need to conduct individualized assessment and intervention on patients, and special attention should be paid to their preoperative activity level and comorbidity.