Objective To summarize and evaluate the best evidence of nonpharmacological intervention in elderly patients with sarcopenia, and provide evidence-based basis for health management of these patients. Methods According to the "6S" evidence pyramid and the principle of PICOS, evidence-based questions were constructed, and evidence on nonpharmacological intervention for sarcopenia in the elderly was searched systematically and retrieved. Then the quality of evidence was evaluated, and the best evidence was extracted and summarized. Results A total of 10 publications were included, embracing 2 guidelines, 2 expert consensus reports and 6 systematic reviews. Eight pieces of evidences were extracted and summarized, and categorized into five aspects: exercise intervention methods, exercise intervention prescription, nutrition intervention, health education and comprehensive intervention. Conclusion It is suggested that evidence users should select evidence most tailored to the clinical environment, professional expertise they have and patients′ preferences, and strictly evaluate the baseline exercise level and nutritional status of patients before applying the evidence.