Objective Explore the effect of varied intake management approaches during painless delivery on progress of labor and the outcome of delivery. Methods A total of 178 low-risk primipara who had been paying regular antenatal visits were selected and arranged to have painless vaginal delivery. According to the admission time, they were divided into an intervention group (n=90) and a control group (n=88). Under the intake dynamic adjustment protocol, the control group was given intravenous rehydration starting from the commencement of active phase in the first stage, while the intervention group was given intravenous rehydration and oral intake management starting from the commencement of the active phase. The differences in progress of labor process and delivery outcomes between the two groups were compared. Results The length of active phase in the first stage, and the lengths of the second and third stage of labor were significantly shorter and the rate of oxytocin use were significantly lower, in the intervention group than those in the control group (P＜0.05,P＜0.01). The rate of natural delivery and the volume of bleeding in the intervention group were lower than those in the control group, but the differences between the two groups were not significant (P＞0.05 for both). There were no significant differences in the incidence rates of vomiting, and the values of blood sugar, serum sodium, and hematocrit between the two groups′ mothers (P＞0.05 for all). There were no significant differences in values pf pH, lactic acid, base excess（BE） and Apgar scores between the two groups′ infants (P＞0.05 for all). Conclusion Intravenous rehydration and oral intake management starting from the commencement of active phase in the first stage could shorten the lengths of labor stages, reduce the use of oxytocin, and improve the rate of natural delivery. The approach does not increase the incidence of maternal vomiting, and has no adverse effect on mothers′blood glucose, blood sodium and neonatal scores.