Objective To explore the management methods for COVID-19 ward and to help the medical staff who are dispatched to Hubei province to battle the virus. Methods Conventional management was conducted during the first week when the medical staff from other parts of China arrived at the COVID-19 ward, then 6S methodology and visual management were implemented for a week. Effects were compared before and after the intervention. Results After the intervention, the time to take materials was significantly shortened, and the satisfaction rate of medical staff was significantly improved (P＜0.01 for all). The scores of nursing quality were increased. Conclusion Implementation of 6S methodology and visual management can help the medical staff from other parts of China adapt quickly to working environment in COVID-19 ward, thus to enhance work efficiency and satisfaction of medical staff.