Objective To improve ICU nurses′ enteral nutrition knowledge-belief-practice, and reduce the incidence of enteral nutrition intolerance for ICU patients. Methods Totally 690 ICU nurses from 12 hospitals in Qingdao were selected, who were then trained on enteral nutrition knowledge, the training methods included theoretical teaching, online teaching, role play, scene reproduction teaching, teaching rounds and practical operation.Self-designed enteral nutrition knowledge-belief-practice questionnaire was utilized to investigate the nurses before and after the training, and the incidence of enteral nutrition intolerance for ICU patients before and after the training was compared. Results After the training, the ICU nurses′ enteral nutrition theoretical knowledge, attitude and belief, and practice ability were significantly higher than those before the training, and the incidence of enteral nutrition intolerance for ICU patients was significantly lower than that before the training (P＜0.01 for all). Conclusion The multiple trai-ning methodsis conducive to improving ICU nurses′ enteral nutrition theoretical knowledge, attitude and belief, and practice ability, and decreasing ICU patients′ incidence of enteral nutrition intolerance.