Objective To evaluate and summarize the best evidence for management of parenteral nutrition after hematopoietic stem cell transplantation （HSCT）, and to provide protocol for clinical intervention. Methods We searched the JBI Database of Systematic Reviews, National Institute for Health and Clinical Excellence, National Guideline Clearinghouse（NGC）, Cochrance Library, PubMed, CNKI, Wanfang database to collect guideline, evidence summary, and expert consensus, etc. Then evidence was summarized after quality evaluation of the literature. Results One evidence summary, two clinical practice guidelines, one systematic review, and two expert consensus statements were included. Fourteen pieces of evidence were summarized, including 4 aspects: parenteral nutrition assessment, prevention of extravasation and catheter-associated complications, prevention of metabolic abnormalities and label management. Conclusion The best evidence summarized in this study can be applied in management of parenteral nutrition in patients undergoing HSCT. It is recommended to use the evidence in clinical practice by considering clinical situation, thus to ensure its applicability and safety.